Significados de ipr039355 em inglês

Electrophoretic mobility-shift assays demonstrated that it bound to the tissue-restricted transcription factor GATA-1.

The nuclear protein FOG-1 binds transcription factor GATA-1 to facilitate erythroid and megakaryocytic maturation.

The transcription factor GATA-1 plays a significant role in erythroid differentiation and association with CBP stimulates its activity by acetylation.

The transcription factor GATA-1 is required for terminal erythroid maturation and functions as an activator or repressor depending on gene context.

The transcription factor GATA-2 is expressed in hematopoietic stem and progenitor cells and is functionally implicated in their survival and proliferation.